Statin unintended effects: Insomnia, insomnia, or sleep-wake cycles could happen

Statins are a class of lipid lowering drugs that reduce disease and mortality in people at high risk of cardiovascular disease. The potent drug is known to cause a number of side effects, including those that can affect your . As?

The accumulating databases of the United States’ Food and Drug Administration’s Adverse Event Reporting System (FAERS) suggest that statin use is associated with an increased risk of disorders, including insomnia.

Hallucinations and nightmares were also seen during statin therapy in other studies.

Researchers have found that fat-soluble statins – including Lipitor, Mevacor, Vytorin, and Zocor – are more likely to cause insomnia or nightmares because they can more easily penetrate cell membranes and cross the blood-brain barrier, which protects the brain from chemicals in the blood.

However, studies of statins and disorders have been conflicting.

A study published in the National Library of Health looked at sleep changes after statin therapy.

The study researched medical information about the effects of statin therapy on sleep changes.

Overall, it found that statin therapy had no significant effect on overall sleep duration or sleep efficiency.

In contrast, statin therapy significantly the time to wake up and the number of times to wake up.

“Meta-regression did not suggest a correlation between changes in waking time and wake-up episodes with duration of treatment and the LDL-lowering effects of statins,” the study found.

It concluded that the results indicated that statins did not have a significant adverse effect on sleep duration and efficiency, but did significantly reduce wake-up times and number of times.

The current evidence from well-conducted research studies of more than 100,000 patients is that statins do not cause insomnia or other sleep disorders when compared to a dummy pill (placebo), said Professor Peter Sever of the British Heart Foundation.

He added, “An important review of these studies, led by BHF Professor Rory Collins, co-authored with me, was published in 2016 in the Lancet.

“Another Lancet study from 2018, in which I was also involved, with 10,000 patients taking a statin (atorvastatin) or placebo, showed significantly fewer sleep disorders in those taking the statin.

“More detailed studies of sleep duration and quality show that statins reduce the frequency of waking and waking time during the night compared to a placebo.”

Statins can be effective in getting your cholesterol under control, but they come with risks. Some common side effects are muscle and joint pain, nausea, and headache.

Serious risks include damage to your muscles, kidneys, and liver. If you have type 2 diabetes, statins can your blood sugar levels.

If you experience any side effects, it is important that you tell your doctor. Sometimes switching to a different statin can help.

Other possible side effects caused by statins can include:

  • a headache
  • Difficult sleep
  • Flushing of the skin
  • Muscle pain, tenderness, or weakness (myalgia)
  • sleepiness
  • dizziness
  • Nausea or vomiting
  • Abdominal cramps or pain
  • Gas or gas
  • diarrhea
  • constipation
  • Rash
  • Low blood platelet counts.

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