Risk elements for pulmonary hypertension mixed with obstructive sleep apnea

Low arterial oxygen pressure (PaO2) during the day is a risk factor for obstructive sleep apnea (OSA) in elderly male patients with pulmonary hypertension (PH), according to a single study published in BMC Pulmonary Medicine.

OSA is more common in people with PH than without. However, the degree of correlation is generally low and therefore OSA is often in the diagnosis, risk stratification, and treatment of PH.

To address the lack of data on the association between PH and OSA, researchers at Fuwai Hospital, National for Cardiovascular Diseases, Chinese Academy of Medical Science developed a study to understand the incidence and clinical characteristics of OSA in patients with PH and examine possible causes of predictors for PH combined with OSA. They included patients with PH diagnosed by right heart catheterization who received overnight cardiorespiratory surveillance from 2018 to 2020.

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Of 140 patients with PH examined, the researchers found that 35 (25%) had OSA, concluding that OSA is relatively common in those with PH, particularly those with chronic thromboembolic PH and those with lung or hypoxia. associated PH. The researchers also found that patients with OSA were predominantly male, with older ages and lower daytime arterial oxygen pressure. A logistic regression analysis was performed to determine the risk factors for OSA in PH patients and it confirmed that higher age, male sex, and lower arterial blood pressure during the day correlated with OSA in PH patients.

According to the researchers, “OSA could worsen PH to some extent, and advanced age, males, and lower PaO2 during the day could predict the presence of OSA.” They added, “Identifying PH patients with OSA can be and treat. ”In addition, the researchers recommended further investigation into the clinical implications of PH with OSA.

relation

Yan L, Zhao Z, Zhao Q, et al. The clinical features of patients with pulmonary hypertension combined with obstructive sleep apnea. BMC Pulm Med. 2021; 21 (1): 378. doi: 10.1186 / s12890-021-01755-5

Subjects:

Obstructive sleep apnea Pulmonary hypertension

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