New monitoring technique over a number of nights can precisely detect obstructive sleep apnea

A new approach to measuring the common sleep-related breathing disorder, obstructive sleep apnea (OSA), estimates that 20% of adults, or about 1 billion people worldwide, have moderate to severe sleep apnea, which can lead to a variety of health problems, as well as driving and driving Dangers to the workplace due to daytime sleepiness.

Professor Danny Eckert of the Adelaide Institute for Sleep Research is researching better treatments for common sleep disorders, including drug options, oral devices, and continuous positive airway pressure (CPAP) for sleep apnea.

The new method of multi-night monitoring at home, tested by an international team led by Flinders University, found that up to half of the participants’ severity varied widely over the six-month study period, suggesting that the Traditional assessments of OSA performed on just one test night can lead to a misdiagnosis in severity.

The results, which are to be published in the American Journal of Respiratory and Critical Care Medicine, that breathing disorders that underlie OSA vary widely from night to night and that monitoring breathing patterns over several nights increases “diagnostic confidence”.

The new study used the results of nightly sleep monitoring in the household of more than 65,000 people worldwide for an average of six months with a new sleep monitoring device under the mattress, the Withings Sleep Analyzer, with the consent of the participants.

“From the 11.6 million nights of data collected, we found that 20% of the study participants showed signs of moderate to severe sleep apnea (characterized by more than 15 breathing disorders per hour),” says Bastien Lechat, researcher at Flinders University.

The large fluctuations in OSA from night to night in many of the people we examined that the diagnosis of OSA based on just one night of observation can be problematic in many cases. “

Bastien Lechat, researcher, Flinders University

Nightly fluctuations in sleep disorders, especially mild and moderate cases, can occur even in severe cases of OSA – all of which can lead to health and safety risks such as heart disease, depression, traffic accidents, and even mortality.

“It’s exciting to think that a simple, non-invasive monitor that sits under your mattress at home has the potential to more accurately classify this debilitating sleep condition,” said Professor Danny Eckert, director of the Adelaide Institute for Sleep Health ( FHMRI.). Sleep) at Flinders University.

The new research highlights that the one-night assessments typically used to diagnose OSA could be improved when combined with non-invasive at-home testing over multiple nights to provide a more accurate diagnosis and optimal treatment options Offer.

Before the recent advances in non-invasive sleep monitoring technology at home, it was not possible to study the night-to-night variation in OSA severity and its potential impact on diagnostic classification and prolonged prevalence estimates in the home on a large scale Study found.

A simple, non-invasive, multi-night evaluation of OSA can be a viable, cost-effective approach to increasing diagnostic success and access, and to complement routine clinical practice, researchers say.

“Multi-Night Prevalence, Variability, and Diagnostic Misclassification of Obstructive Sleep Apnea” (2021) by Flinders researchers Bastien Lechat, Ganesh Neik, Amy Reynolds, Atqiya Aishah (FHMRI Sleep Health, UNSW NeuRA), Hannah Scott, Kelly Loffler, Andrew Vakulin, Pierre Escourrou (Center Interdisciplinaire du Sommeil), Doug R. McEvoy, Robert Adams, Peter Catcheside, and Danny Eckert was published in the American Journal of Respiratory and Critical Care Medicine DOI: 10.1164 / rccm.202107-1761OC.

Source:

Journal reference:

Lechat, B., et al. (2021) New and emerging approaches to better define sleep disorders and their consequences. Frontiers of Neuroscience. doi.org/10.3389/fnins.2021.751730.

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