(IXHL) – Incannex’s Cannabinoid Combo Product Reduces AHI In Sleep Apnea Patients

Incannex Healthcare Limited (NASDAQ: IXHL) has completed a preliminary analysis of data from its Phase 2 trial of a cannabinoid combination product, IHL-42X, for obstructive sleep apnea (OSA).

  • The clinical trial assessed three doses of IHL-42X at reducing the apnea hypopnoea index (AHI), the main diagnostic and monitoring criteria for OSA, compared to placebo.
  • For all IHL-42X treatment periods (using low, mid, and high doses), the average AHI was 23.81, a 44.4% reduction from the baseline score of 42.84, compared to a 6.4% reduction in the placebo group.
  • Related: Medicinal Cannabis And Psychedelics Company Incannex Lists American Depositary Shares On Nasdaq
  • 60% of participants experienced a reduction in AHI of over 50% (55.0% to 91.5%) and a resulting AHI of less than 20 during at least one treatment period of one dose strength of IHL-42X.
  • 20% of participants experienced a reduction in AHI of over 80% (82.7% to 91.5%) relative to baseline.
  • Incannex is preparing for a pre-IND meeting with the FDA on the plan for IHL-42X, scheduled on May 11.
  • The meeting will guide what data is required to open an Investigational New Drug (IND) application for a larger pivotal phase 2 trial.
  • Price action: IXHL shares closed at $10.46 on Tuesday before trading halt.

Leave a comment

Your email address will not be published. Required fields are marked *